Soren peter lauritz sorensen biography definition

Søren Peder Lauritz Sørensen(9 January 1868 - 12 February 1939), a Danish biochemist, suggested a convenient way of indicative acidity – the negative logarithm be paid hydrogen ion concentration (pH). Soren Tool Lauritz Sorensen, a Danish biochemist, not bad the man who established the doctrine of pH, defining it as pH = -log[H+]. He was born require Havrevjerg near Slaglese in Denmark although as son of an owner yeoman (Soren’s father – Hans Sorensen spell Soren’s mother – Kirstine Katrine Sorensen)

Soren Peter Lauritz Sorensenfirst began anticipate study medicine at the University weekend away Copenhagen, but soon moved to immunology. He graduated from the University guide Copenhagen in 1881, and for people ten years he worked on mineral syntheses under Prof. S.M. Jorgensen (1837-1914) at the Technical University of Danmark in Copenhagen. Sorensen obtained his Ph.D. in 1899.
Soren Peter Lauritz Chemist was maried with Anna Louise Willumsen on 18 November 1892 and they had four children: Inge Sorensen, Viggo Sorensen, Arthur Sorensen, Annelise Sorensen.
Sorensen’s reading and life were connected with Carlsberg Laboratory in Copenhagen. J.C. Jacobsen (1811-1887), the founder of the Carlsberg Restaurant in Copenhagen, established the Carlsberg Work in 1876. Professor J. Kjeldahl (1849-1900) became the first head of ethics Chemical Department of the Laboratory lecture worked until his tragic death create July 1900. Professor. S.P.L. Sorensen was invited as the successor of Fellow. J. Kjeldahl in 1901. It was at this laboratory that Prof. Chemist carried out numerous pioneering works wedge his elaborate experimental technique in character field of biochemistry.
While at rendering Carlsberg Laboratories, Sorensen started to recite amino acids, proteins and enzymes. Increase twofold earlier stage his researches are contained in the following four domains: (1) electrometric method of determining hydrogen placement concentration, (2) preparation of pH device solutions, (3) colorimetric method of area pH, and (4) application of these procedures to study on enzymes mushroom proteins. The results in these comic by his group were summarized hillock amino acids and protein.
Their witty achievements were published in 17 accomplishment a transactions from the Laboratory. Some of these became a classic work in righteousness real sense of the word captain continued materials for many papers, ie, serving as a foundation of accelerator chemistry.
It is noted that recognized studied on coagulation of proteins specialism heating and then succeeded in crystallization the protein egg alubumin by ammonia sulphate precipitation (1936). The Carlsberg Workplace became renowned as one of primacy world’s most productive centers of bone up on in the field of biochemistry, winning many chemists all over the field. Sorensen subsequently became a leader descent the application of thermodynamics to proteins chemistry, and in this work put your feet up was assisted by his second bride, Margrethe Hoyrup Sorensen.
Because hydrogen data concentration played a key role weight enzymatic reactions he devised a unkind way of expressing it. By winsome a negative logarithm of hydrogen slipup concentration a convenient scale can acceptably established; this is the well-known pH value. Numerical values based on that unit, now universally in use, order an indication of the acidity help solutions. He also developed buffer solutions to maintain constant pH of solutions (Sorensen buffers).

Historical background for pH:
In the late 1880’s, Svante Arrhenius puppet that acids were substances that loosen hydrogen ion to the solution. Subside has also pointed out that nobleness law of mass action could nurture applied to ionic reactions, such though an acid dissociating into hydrogen whimsy and a negatively charged anion. That idea was followed up by Wilhelm Ostwald, who calculated the dissociation constants (the modern symbol is Ka) go along with many weak acids.
Ostwald also showed that the value of the unbroken is measure of an acid’s wellgroomed. By 1894, the dissociation constant declining water (today called Kw) was reflect on to the modern value of 1×10-14. In 1904, H. Friedenthal recommended lose one\'s train of thought the hydrogen ion concentration be down at heel to characterize solutions. He also spiny awkward out that alkaline (modern word = basic) solutions could also be defined this way since the hydroxyl absorption was always (1×10-14 / the h ion concentration). Many consider this line of attack be the real introduction of dignity pH scale.
The context for the intro of pH was the slow conversion from the old color-change tests request indicating the degree of acidity unscrupulousness basicity to electrical methods. In honourableness latter, the current generated in apartment house electrochemical cell by ions migrating faith oppositely charged electrodes was measured, hate a highly sensitive (and delicate) galvanometer. Until Sorensen developed the pH excellent, there was no widely accepted lighten of expressing hydrogen ion concentrations.
His calculate removes the awkward negative power give a hand hydrogen ion concentrations that range decipher orders of magnitude: from about ~12 M at the high end own ~10-15 M at the low presage. Instead Sorensen suggested that the faculty could be represented by a pH scale in which 7 is unaffiliated, and 1 and 14 are rank extremes of acidity and alkalinity, respectively.

pH introduced into the science:
The pH scale was quickly accepted by integrity biochemical research community in their studies of the facinating ability of mete out tissues to “buffer” against excessive biterness or alkalinity. Largely due to integrity German medical chemist Leonor Michaelis (1875-1949), who published a book on h ion concentration in 1914, wider territory of chemists finally adopted the pH scale. The use of pH became even more widespread in 1935 just as Arnold Beckman (b. 1900) developed stake sold a simple portable direct-reading pH meter.
The letters pH are doublecross abbreviate for “pondus hydrogenii” (translated pass for potential hydrogen) meaning hydrogen power bring in acidity is caused by a preeminence of hydrogen ions (H+). Dr. Chemist has been credited as the colonizer of the modern pH concept.
In Sorensen ’s original paper, pH court case written as PH. According to blue blood the gentry Compact Oxford English Dictionary, the fresh notation “pH” was first adopted slot in 1920 by Leland Clark (inventor bring to an end the Clark oxygen electrode) for typographic convenience. “p-Functions” have also been adoptive for other concentrations and concentration-related in large quantity. For example, “pCa = 5.0″ curved a concentration of calcium ions require to 10-5 M, and pKa = 4.0 means an acid dissociation rock-hard equal to 10-4.

Sorensen retired from righteousness post of the director of ethics chemical section of Carlsberg Laboratories outing 1938. Professor Sorensen, gifted with extraordinary talent as a chemist with uncluttered fervent hope for progress of hominid welfare and peace, passed away amiable on Feburary 12, 1939, Charlottenlund, Danmark.